HeartGenetics, Genetics and Biotechnology SA is a Portuguese biotech company that developed “solutions in a box”, including genetic tests and computational tools designed to support clinical diagnosis and the prevention of cardiovascular diseases, pharmacogenetics and nutrition.
Based on a DNA MICROCHIP array platform for genetic analysis, our team of researchers has developed genetic tests for several cardiac pathologies [learn more]. Our genetic test reports are simple and easy to interpret, providing important information to support medical doctors in their clinical decisions.
Clinical Reporting and Expert Systems
The genetic data is analyzed by our proprietary expert system “HEARTDECODE”, providing highly accurate and reproducible analysis and the integration of both genetic and clinical data. The system is constructed of efficient and scalable algorithms for clinical data analysis and processing, and enables the efficient generation of an unlimited number of clinical reports, reducing the time and complexity of the genetic test.
HeartGenetics is a VC-backed company since April 2013, by Portugal’s unique world-class VC players.
We believe that current genomic technologies and computational advances will fundamentally change medicine practice and improve human health in the near future, by making available innovative knowledge that will help healthcare providers to promote wellness, prevent illness and diagnose disease.
To play a leading role in changing the status quo of the use of genetic information, by bringing up innovative knowledge to help healthcare providers prevent heart disease with heart-healthy lifestyle changes and medicines.
New and certified medical devices, AI tools and genetic testing kits, that make genetic testing simple, actionable and cost-effective.
HeartGenetics institutional motto is:
“Knowledge through genetics”
We have a multidisciplinary team of PhDs and specialists in genetics, bioinformatics and molecular biology that is 100% committed to the quality of our services.
Ana Teresa Freitas
Ana Teresa Freitas
CEO (Chief Executive Officer)
Ana Teresa (PhD) is co-founder/shareholder of HeartGenetics.
She holds a PhD in Computer Engineering and a Master degree in Electronics Engineering. She attended the Advanced Management Program on Innovation and Entrepreneurship from Católica Lisbon – BES, School of Business and Economics (2013).
Her main expertise is on the areas of Computational Biology, Human genetics, Algorithms and Data Mining. For the last 15 years she has co-authored about 90 papers in journals and international conferences in the areas of computational biology and bioinformatics, 2 book chapters, supervised 6 PhDs and more than 14 master students.
As a researcher at INESC-ID, she was the head (2009-2014) of the Knowledge Discovery and Bioinformatics research group (KDBIO http://kdbio.inesc-id.pt. She also coordinated international projects under FP7 and many Portuguese National projects.
As a Full Professor at Técnico Lisboa, University of Lisbon, Department of Computer Science and Engineering, she created the Computational Biology course; she is presently the coordinator of the Scientific Area of Programming Methodology and Technology at Department of Computer Science and Engineering.
She is Vice-chair of the Board for 2017 and Board member (representing Portugal) at ESFRI ELIXIR (http://www.elixir-europe.org/).
CTO (Chief Technology Officer) - Genetics
Susana (PhD) is co-founder/shareholder of HeartGenetics.
She is also an Assistant Professor at Universidade Lusófona de Humanidades e Tecnologias and was an Invited Professor at Faculdade de Farmácia, Universidade de Lisboa in Molecular and Human Genetics.
Her current interests involve tackling molecular and cellular mechanisms of cardiovascular genetic diseases and correlating with clinical profile. Also following the topic of pharmacogenetics.
She has co-supervised 14 master students and co-authored about 20 papers in journals and national /international conferences and 1 book chapter in the area of genetics and molecular biology. She has coordinated one national project (cardiogenetics) and participated in more than 10 national projects.
Hélder Simão Barbosa
Hélder Simão Barbosa
Head of Business Development
Hélder received his PhD in Biotechnology (2009) from University of Minho (PT) and University of Cambridge (UK). His project was in the field of DNA downstream processing, having published several papers in this field.
Prior to working at Heartgenetics, Hélder worked in 3D microarray technology at Instituto Superior Técnico (PT) and at Rensselaer Polytechnic Institute (USA).
Helder holds The Lisbon MBA (2013) and he was awarded several prizes, including the Malcolm Lilly Award (2012), attributed by the European Society of Biochemical Engineering Sciences to a promising young scientist working in the field of bioengineering.
Helena Vazão received her PhD in Cellular Biology (2012) from University of Coimbra (PT) and in collaboration with the Massachusetts Institute of Technology (USA). She developed platforms to translate scientific discoveries in medical applications. The main area of study involved vascular diseases, diabetes and myocardial infarction. She described the first platform for high-throughput identification of small molecules that affect human embryonic vascular development. The discovery includes the combination of toxicology and microfluidics technology. Several papers have been published as result of this expertise.
Prior to working at HeartGenetics, Helena worked as Post Doctoral researcher at the Biomaterials and Stem Cell-Based Therapeutics Laboratory from Center for Neuroscience and Cell Biology. Her project was focused in the development of approaches to improve the differentiation, maturation and biological activity of vascular cells derived from human stem cells. She also has a previous experience in Hematology – red blood cells abnormalities. The project was developed in two Hospital Hematology Units (Coimbra (PT) and Oxford (U.K.)). At the same time she was involved in the development, implementation (planning, theoretical and practical training of doctors and nurses) and laboratorial execution of a hemoglobinopathies screening in Portugal.
Helena was awarded with fellowships and prizes attributed by Aveiro University (2002), the Portuguese Science and Technology Foundation (2007, 2008 and 2012), Eurosystem (2010), Marie Curie (2009) and Award Professor Doutor Amândio Tavares (2008).
Gonçalo Antunes received his PhD in Computer Science and Engineering (2015) from the Instituto Superior Técnico of the Universidade de Lisboa (PT). His main area of focus was on knowledge representation and analysis techniques, conceptual modelling, and system architectures. He has published several papers in international peer reviewed journals and conferences on these topics. He holds a BSc and an MSc in Computer Science and Engineering from the same university.
Prior to working at HeartGenetics, Gonçalo was a Post-Doctoral researcher at Information and Decision Support Systems group at the Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento em Lisboa (INESC-ID). He was responsible for coordinating the technical infrastructure of the group and for providing technical support to several projects of the group.
From 2008 to 2016, Gonçalo was involved in several projects, at the national and European levels. National projects include DataStorm and GRITO. International projects include SHAMAN, TIMBUS, BenchmarkDP and ELIXIR Excelerate. His tasks many times involved the preparation of the preparation of the project proposals, and the coordination and execution of work packages and tasks.
From 2009 to 2012, Gonçalo was an Invited Assistant Professor at the Faculdade de Ciências Sociais e Humanas of the Universidade Nova de Lisboa.
José Caldas holds a PhD in bioinformatics and machine learning from Aalto University, as well as BSc and MSc degrees in Computer Science and Engineering from Instituto Superior Técnico (University of Lisbon).
Prior to working at HeartGenetics, José was co-founder and CEO of Insightomics, a bioinformatics software company. We was also a researcher in the KDBIO group at INESC-ID Lisbon.
José has participated in multiple projects related to applying state-of-the-art machine learning methodologies to the analysis of large-scale transcriptomics data. He has also participated in oncology and cardiology translational medicine projects, aimed at bringing transcriptional and genetic biomarkers to the clinic. Besides bioinformatics and machine learning, José is also currently interested in information visualization and web technologies.
Laboratory Unit Director
Ana Silva is Lab Unit Director at HeartGenetics. She holds a master degree in Biotechnology and was a Research Fellow in Faculty of Pharmacy, University of Lisbon, were, in collaboration with IST, she studied the molecular pathways involved in cell response to newly-synthesized compounds with anti tumor activity.
Ana was CTO and board member in the biotechnology start-up Ibergene, were she was responsible for the development and implementation of personalized genetic tests and for the company’s laboratory and technical protocols. She was also involved in the business plan development and fund raising for the Ibergene spin-off project.
Laboratory Unit Director
Daniel is a Lab Unit Director at HeartGenetics.
He received his BSc in Biochemistry and his MSc in Molecular Genetics and Biomedicine from Faculty of Sciences and Technology, New University of Lisbon (UNL).
During his graduation, Daniel worked as a researcher in Instituto de Tecnologia Química e Biológica (UNL) performing heterologous protein expression and stopped-flow kinetics in anaerobic atmosphere.
While a research fellow at Faculty of Pharmacy, University of Lisbon (UL), he studied the molecular mechanisms underlying the antitumor potential of metal complexes, in a partnership with the Centro de Química Estrutural (IST, UL).
Apart from articles in international peer reviewed journals, Daniel also co-authored a book chapter on nanomedicine.
Miguel participated and was responsible for critical IT projects, mainly in the financial sector, and across the development cycle: requirements analysis, application design, development and testing.
Technical background involves several platforms and languages, and applications such as information systems or code optimization.
He also has presales experience (IT products and services): strategy, planning, presentations, proposals and customer management.
Rafael has a computer science background from Instituto Superior Técnico. Prior to HeartGenetics, Rafael has worked in web development and in maintenance of computer networks.
Rafael has been awarded several awards related with computer science, namely two times 1st place in the National Olympics of Informatics, two times 1st place in Inter-University Programming Marathon (as a team), 2nd place in South West European Regional Competition, and 3rd place at Iberoamerican Informatics Competition.
He received his MSc in Computer Science from Instituto Superior Técnico, Universidade de Lisboa, having Software Engineering and Artificial Intelligence as expertise areas.
Hugo is passionate about technology and entrepreneurship and he participated in several entrepreneurship gatherings where he gained experience on accelerating and pitching ideas. He went through the business model design of some of his own projects, trying to bring them to life, experiencing the iterative and entropic nature of customer-driven development, having also collaborated with other startups.
After concluding his master he was a grant holder at INESC-ID continuing his Master Thesis research work on Social Network Analysis and Big Data.
Maria Raimundo is a current PhD student at MIT Portugal in Bioengineering. Her study focuses on better understanding value propositions and market positioning of genetic testing companies.
She holds a Master’s degree in Bioentrepreneurship from Karolinska Institute and a Bachelor’s degree in Biomedical Engineering. She worked at the United Nations helping in the implementation of mobile health technologies in developing countries, at the University of Basel doing sports technology research and at a Swiss AI start-up in delivering innovative product ideas to Fortune top 500 companies.
Senior Laboratory Technician
She received a Bsc in Biochemistry from Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa (UNL) and a Msc in Pharmaceutical Sciences from Faculdade de Farmácia da Universidade de Lisboa (UL).
Prior to working in HeartGenetics, Sandra worked in a clinical pathology laboratory where she was responsible for the biochemistry unit. Sandra was involved in Quality Management System, having been responsible for the implementation of ISO 9001.
HeartGenetics has been supported during the years by a strong team of well- known scientists and medical doctors. These members of the advisory board are internationally recognized as experts in their own field and have been working in a close collaboration with the company.
PhD in Computer Science from UC Berkeley;
CO-founder of ALGOS and KDBIO research groups at INESC-ID;
President of Instituto Superior Técnico
President of the European Society of Cardiology (ESC);
Dean of Faculty of Medicine, University of Lisbon, Portugal
PhD in Human Genetics and Pathology;
Director of Laboratório de Citogenética e
Genómica at Centro de Neurociências, Universidade de Coimbra
Medical doctor (PhD) on Cardiology;
Director of Laboratório de Ecocardiografia at Hosp. da Luz; Member of the European Society of Cardiology
Medical doctor, Specialist in Otolaryngology;
CEO at Schönermark Kiel Horn colleagues mbH;
Professor of Health Care Management at the Hannover Medical School
Awards & Recognitions
The Fundación Everis awarded HeartGenetics approach to genetic testing with the International Innovation Prize in 2013.
HeartGenetics was selected as one of world’s ten most innovative healthcare startups during the World Health Summit 2015.
EIT GoGlobal DigiHealth is a programme designed to prepare and support entrepreneurs working in digital health care to expand their vision and business to the US market. HeartGenetics was award with a participation in this program in 2016 in Silicon Valley.
EIT GoEurope is a programme designed to prepare and support entrepreneurs to expand their vision and business to the EU market. HeartGenetics was award, 2016, with a 50K Euros grant to support its go-to-market in Europe.
Health 2.0 – Traction 2016: HeartGenetics was finalist and had the possibility to pitch at Health 2.0 Santa Barbara, SV