{"id":14379,"date":"2017-06-30T08:24:05","date_gmt":"2017-06-30T08:24:05","guid":{"rendered":"https:\/\/www.heartgenetics.com\/news\/heartgenetics-launches-new-test-in-oncology-oncoalvo\/"},"modified":"2017-06-30T08:24:05","modified_gmt":"2017-06-30T08:24:05","slug":"heartgenetics-launches-new-test-in-oncology-oncoalvo","status":"publish","type":"newslist","link":"https:\/\/www.heartgenetics.com\/pt\/news\/heartgenetics-launches-new-test-in-oncology-oncoalvo\/","title":{"rendered":"HeartGenetics launches new test in Oncology – OncoAlvo\u00ae"},"content":{"rendered":"

(vers\u00e3o em Portugu\u00eas em baixo)\u00a0<\/span><\/p>\n

HeartGenetics<\/strong> continues to increase its portfolio of genetic tests, particularly within the pharmacogenetics area. <\/span>OncoAlvo\u00ae<\/span><\/strong> is a new genetic study of the anti-EGFR antibody therapy response in metastatic colorectal carcinoma<\/strong>. With this new test, medical oncologists will be able to know what is the best and most effective treatment for each patient.<\/span><\/p>\n

90% to 80% of patients with colorectal cancer do not respond well to therapy directed to EGFR receptors, being resistant to this therapy mainly due to the presence of mutations in the RAS genes.<\/span><\/p>\n

OncoAlvo\u00ae<\/span><\/strong> evaluates more than 170 genetic mutations<\/strong>, including those recommended by the European Society of Medical Oncology (ESMO<\/strong>), the American Society of Clinical Oncology (ASCO<\/strong>) and the NICE<\/strong> Medical Guidelines (UK). OncoAlvo\u00ae<\/span><\/strong><\/span>\u00a0evaluates the<\/span> KRAS<\/strong>, NRAS<\/strong>, BRAF<\/strong>, EGFR<\/strong>, ERBB2<\/strong>, <\/span><\/i>and<\/span> PIK3CA<\/i><\/strong> genes.<\/span><\/p>\n

OncoAlvo\u00ae<\/span><\/strong> genetic panel was developed in a join collaboration<\/strong> with the IPO-Porto<\/a> and is scientifically validated and proven to its clinical utility with more than 500 patients.<\/span><\/p>\n

The genetic study is performed through the analysis of single directed mutations with an accuracy of 99%<\/strong> through the innovative iPLEX MassARRAY\u00ae system. <\/span><\/p>\n

\"\"<\/a><\/p>\n

Cancer is personal, so is its treatment.<\/strong> <\/span><\/p>\n

OncoAlvo\u00ae<\/span><\/strong><\/span><\/p>\n

 <\/p>\n

Get in contact<\/a> to know more.<\/p>\n

Flyer OncoAlvo\u00ae<\/a><\/p>\n

 <\/p>\n

—-<\/p>\n

Lan\u00e7amento de um novo teste gen\u00e9tico \u2013 o teste OncoAlvo\u00ae<\/strong><\/span><\/p>\n

A HeartGenetics<\/strong> continua a aumentar o portf\u00f3lio de testes gen\u00e9ticos, nomeadamente dentro de \u00e1rea da farmacogen\u00e9tica. O novo teste designado de OncoAlvo\u00ae<\/span><\/strong>\u00a0<\/strong>permitir\u00e1 a realiza\u00e7\u00e3o de um estudo gen\u00e9tico para avalia\u00e7\u00e3o da resposta personalizada \u00e0 terapia por \u00a0anticorpos anti-EGFR em carcinoma colorectal metast\u00e1tico<\/strong>. Com este novo teste, m\u00e9dicos oncologistas poder\u00e3o saber qual o melhor e o mais eficaz tratamento para cada paciente. <\/span><\/p>\n

Actualmente cerca de 90% a 80% dos pacientes com cancro colorectal n\u00e3o respondem bem \u00e0 terapia direcionada aos receptores EGFR, sendo resistentes a esta terapia maioritariamente devido \u00e0 presen\u00e7a de muta\u00e7\u00f5es nos genes <\/span>RAS<\/span><\/i>.<\/span><\/p>\n

O novo teste OncoAlvo\u00ae<\/span><\/strong>\u00a0<\/strong>vai permitir realizar em simult\u00e2neo a avalia\u00e7\u00e3o de mais de 170 muta\u00e7\u00f5es gen\u00e9ticas<\/strong>, incluindo as recomendadas pela ESMO<\/strong> (<\/span>European Society for Medical Oncology<\/span><\/i>), ASCO<\/strong> (<\/span>American Society of Clinical Oncology<\/span><\/i>) e as <\/span>NICE<\/strong> Medical Guidelines<\/span><\/i> (UK). Entre os genes avaliados incluem-se<\/span> os genes <\/span>KRAS<\/strong>, NRAS<\/strong>, BRAF<\/strong>, EGFR<\/strong>, ERBB2<\/strong>, <\/span><\/i>e<\/span> PIK3CA<\/strong>. <\/span><\/i><\/p>\n

Este painel gen\u00e9tico,desenvolvido em parceria com o IPO-Porto<\/strong>, \u00a0est\u00e1 validado cientificamente e viu comprovada a sua utilidade cl\u00ednica atrav\u00e9s da an\u00e1lise de mais de 500 amostras biol\u00f3gicas<\/strong>.<\/span><\/p>\n

O estudo gen\u00e9tico \u00e9 efectuado atrav\u00e9s da an\u00e1lise de muta\u00e7\u00f5es \u00fanicas direcionadas utilizando a tecnologia iPLEX MassARRAY\u00ae, apresentando uma precis\u00e3o superior a 99%. <\/strong><\/span><\/p>\n

O cancro \u00e9 pessoal, tamb\u00e9m o seu tratamento. <\/strong><\/p>\n

OncoAlvo\u00ae<\/span><\/strong><\/p>\n

 <\/p>\n

 <\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

Get in contact to know more. <\/b><\/p>\n","protected":false},"excerpt":{"rendered":"

(vers\u00e3o em Portugu\u00eas em baixo)\u00a0 HeartGenetics continues to increase its portfolio of genetic tests, particularly within the pharmacogenetics area. OncoAlvo\u00ae is a new genetic study […]<\/p>\n","protected":false},"featured_media":9088,"menu_order":0,"template":"","class_list":["post-14379","newslist","type-newslist","status-publish","has-post-thumbnail","hentry"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.heartgenetics.com\/pt\/wp-json\/wp\/v2\/newslist\/14379","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.heartgenetics.com\/pt\/wp-json\/wp\/v2\/newslist"}],"about":[{"href":"https:\/\/www.heartgenetics.com\/pt\/wp-json\/wp\/v2\/types\/newslist"}],"version-history":[{"count":0,"href":"https:\/\/www.heartgenetics.com\/pt\/wp-json\/wp\/v2\/newslist\/14379\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.heartgenetics.com\/pt\/wp-json\/wp\/v2\/media\/9088"}],"wp:attachment":[{"href":"https:\/\/www.heartgenetics.com\/pt\/wp-json\/wp\/v2\/media?parent=14379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}