Genetics and Sports Performance and Nutrition
Nowadays, everyone is interested in practicing fitness activities or in attending sports competitions, whether for physical appearance, health, or motivational reasons. However, lack of progress, injuries or unattained fitness goals are still recurrent issues that eventually lead to dropping out.
Recent scientific studies reinforce the importance of integrating genetic information with each individual’s physical aptitude, injury predisposition, recovery and, of course, micronutrient sensitivities and needs, and antioxidant capacity to establish a more:
> Efficient training programme
> Sustainable and healthy muscle building and toning
> Personalised fitness modalities suggestions
> Personalised nutritional plan
MyFitnessGenes® is a 99% accurate and actionable genetic test that informs about how each individual’s unique genetic profile impacts the definition of a more personalised training and nutrition programme in order to achieve an optimised athletic performance.
The MyFitnessGenes® report:
> Supports the definition of a tailored training strategy.
> Takes advantage of the individual genetic potential to help reach fitness goals and obtain long-lasting results.
> Provides information about the most appropriate activities, training intensity and regime.
> Informs about protective measures for improved recovery and for injury risk prevention.
> Delivers actionable and personalised recommendations with great impact on daily dietary choices, in order to minimize deficiencies in micronutrients and the undesirable effects of caffeine in individuals who are genetically predisposed to them.
> Simplifies genetic information to be applied by professionals without being genetic experts.
MyFitnessGenes® is a state-of-the-art and up-to-date genetic test that accurately analyses 82 genetic variants of 70 genes, with a significant impact on the following 3 main areas:
MyFitnessGenes® makes use of the most recent and rigorous scientific studies, allowing personal trainers and nutritionists to have unique insights into each person’s athletic capacity and micronutrient metabolism.
The DNA, extracted from a saliva sample, is analysed to evaluate 82 genetic variants from 70 genes. These genes are specifically associated with athletic performance for power, endurance or power-endurance mixed activities, VO2 max, muscle building, injury, recovery, and nutritional requirements and sensitivities.
ACE, ACSL1, ACTN3, ACVR1B, ADAMTSL3, ADORA2A, ADRB2, AGT, AGTR2, , AHR, AMPD1, AQP1, ATP2B1, BDKRB2, BHMT, CA1, CASR, CAT, CCL2, CCR2, COL1A1, COL5A1, COMT, CUBN, CYP1A1, CYP1A2, CYP24A1, DGKD, DMGDH, FADS1, FUT2, GABPB1, GCKR, GDF5, GPX1, HFE, HIF1A, HOMER1, IGF1, IL15RA, IL6, IL6R, IRS1, LOC101928338, MMP3, MTHFR, MUC1, NBDY, NFE2L2, NOS3, NRF1, PPARA, PPARG, PPARGC1A, PPCDC, SHROOM3, ALC16A1, SLC30A8, SOD2, TCN1, TF, TFR2, TGFA, TMPRSS6, TNF, TRPM6, UCP2, UCP3, VCAN, VEGFA
MyFitnessGenes® is based on the most relevant and statistically significant genotype-phenotype studies. The gene panel was selected according to each gene’s biological relevance towards traits of interest regarding athletic potential (e.g., power ability, aerobic capacity) and nutritional requirements and sensitivities.
 PLoS ONE 8, e54685, 2013
 The Genetics of Sports Injuries and Athletic Performance, 3(3), 173-189 2013
 Journal of Exercise Nutrition & Biochemistry, 19(2), 49-53, 2015
 International Journal of Sports Physiology and Performance, 9(1), 173-180, 2014
 BMC Genetics, 15, 58, 2014
 Bio Sport, 33(2), 117-126, 2016
 BMC genomics, 18.8, 835, 2017.
 Human molecular genetics, 22(19), 3998-4006, 2013.
 Human molecular genetics, 24(5), 1469-1477, 2015.
 PLoS Genet, 9(9), e1003796, 2013.
 Nature communications, 5(1), 1-11, 2014.
 Scandinavian journal of medicine & science in sports, 25(2), 166-174, 2015.
 Frontiers in Genetics, 11, 711, 2020.
 Nature communications, 8(1), 1-13, 2017.
 The American journal of clinical nutrition, 109(2), 276-287, 2019.